Customized iPad App for British Prime Minister

By SiliconIndia, Wednesday, 28 December 2011, 23:33 Hrs

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'); manageControls(currentPosition); $('.control') .bind('click', function(){ currentPosition = ($(this).attr('id')=='rightControl') ? currentPosition+1 : currentPosition-1; manageControls(currentPosition); $('#slideInner').animate({ 'marginLeft' : slideWidth*(-currentPosition) }); }); function manageControls(position) { if(position==0) { $('#leftControl').hide() document.getElementById("p2").style.display = "block"; document.getElementById("p3").style.display = "block"; $('#rightControl').show() } else if(position==numberOfSlides-2 ) { $('#leftControl').show() document.getElementById("p3").style.display = "block"; $('#rightControl').show() } else if(position==numberOfSlides-1 ) { $('#leftControl').show() document.getElementById("p2").style.display = "block"; $('#rightControl').hide() } } });


Bangalore: British Prime Minister, David Cameron is going to get a personalized App for his iPad to stay ahead and updated in Government affairs. This App will be a one-stop store for all the happening related to country?s facts, issues and performance.? There is also a rumor that this App will be available to the public after a while.


The London Times and The Telegraph has stated that ?Mr Cameron will be able to see at a glance the latest NHS waiting-list figures, crime statistics, unemployment numbers and myriad other data which, in the short term, could provide quite grim reading?. And ?The programmers inside Cabinet Office are working on the App for the Prime Minister that will bring together the latest information from across government with his favorite new sources?.


The intended App is said to have ?real time? news from Google, Twitter and other news sources. This implies that the App will rely on the open data stream which already exists on internet. The secrecy still prevails whether this will be a real App or just another highly protected webpage exclusively for British Prime Minister.


Reports say that the App is going to the launched in March 2012. We suppose this long delay is due to the long security testing process it has to pass through, as the App may include confidential government data. ?Is India Government planning something like this which is using the high end technology of the gadget and App world to channelize government information????


Source: http://feedproxy.google.com/~r/si-techproduct/~3/Unn2JOstB_w/Customized_iPad_App_for__British_Prime_Minister-nid-101771.html

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Deal of the Day ? Samsung Galaxy Nexus for Verizon

Today’s LogicBUY Deal is the Samsung Galaxy Nexus for the Verizon system for $199.99.? This is the first phone running the new Android OS 4.0 Ice Cream Sandwich.? Features:? 4.65″ 720×1280 HD Super AMOLED display, a dual-core 1.2GHz TI OMAP 4460 processor, 1GB RAM, 32GB built-in storage, 5MP rear camera (1080p video capable), 1.3MP front [...]

Source: http://the-gadgeteer.com/2011/12/30/deal-of-the-day-samsung-galaxy-nexus-for-verizon/

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'Rare' brain disorder may be more common than thought

Tuesday, December 27, 2011

A global team of neuroscientists, led by researchers at Mayo Clinic in Florida, have found the gene responsible for a brain disorder that may be much more common than once believed. In the Dec. 25 online issue of Nature Genetics, the researchers say they identified 14 different mutations in the gene CSF1R that lead to development of hereditary diffuse leukoencephalopathy with spheroids (HDLS). This is a devastating disorder of the brain?s white matter that leads to death between ages 40 and 60. People who inherit the abnormal gene always develop HDLS. Until now, a definite diagnosis of HDLS required examination of brain tissue at biopsy or autopsy.

The finding is important because the researchers suspect that HDLS is more common than once thought and a genetic diagnosis will now be possible without need for a brain biopsy or autopsy. According to the study?s senior investigator, neurologist Zbigniew K. Wszolek, M.D., a significant number of people who tested positive for the abnormal gene in this study had been diagnosed with a wide range of other conditions. These individuals were related to a patient known to have HDLS, and so their genes were also examined.

?Because the symptoms of HDLS vary so widely ? everything from behavior and personality changes to seizures and movement problems ? these patients were misdiagnosed as having either schizophrenia, epilepsy, frontotemporal dementia, Parkinson?s disease, multiple sclerosis, stroke, or other disorders,? says Dr. Wszolek. ?Many of these patients were therefore treated with drugs that offered only toxic side effects.

?Given this finding, we may soon have a blood test that can help doctors diagnose HDLS, and I predict we will find it is much more common than anyone could have imagined,? he says.

Dr. Wszolek is internationally known for his long-term efforts to bring together researchers from around the world to help find cases of inherited brain disorders and discover their genetic roots.

Dr. Wszolek?s interest in HDLS began when a severely disabled young woman came to see him in 2003 and mentioned that other members of her family were affected. The diagnosis of HDLS was made by his Mayo Clinic colleague, Dennis W. Dickson, M.D., who reviewed the autopsy findings of the patient?s uncle, who had previously been misdiagnosed as multiple sclerosis, and subsequently, Dr. Wszolek?s patient and her father. All members of the family had HDLS.

Dr. Dickson had identified other cases of HDLS from Florida, New York, Oregon and Kansas in the Mayo Clinic Florida brain bank and knew of a large kindred in Virginia with similar pathology, based upon a presentation at the annual meeting of the American Association of Neuropathologists. With concerted efforts, Dr. Wszolek and collaborators at University of Virginia were able to obtain DNA samples from the Virginia kindred. Dr. Wszolek also sought other cases, particularly those that had been reported in the neuropathology literature, and he was able to obtain samples from Norway, the United Kingdom, Germany and Canada, and other sites in the U.S. He and his team of investigators and collaborators have since published studies describing the clinical, pathologic and imaging characteristics of the disorder, and they have held five international meetings on HDLS.

In this study, which included 38 researchers from 12 institutions in five countries, the study?s first author, Rosa Rademakers, Ph.D., led the effort to find the gene responsible for HDLS. Her laboratory studied DNA samples from 14 families in which at least one member was diagnosed with HDLS and compared these with samples from more than 2,000 disease-free participants. The gene was ultimately found using a combination of traditional genetic linkage studies and recently developed state-of-the art sequencing methods. Most family members studied ? who were found to have HDLS gene mutations ? were not diagnosed with the disease, but with something else, thus emphasizing the notion that HDLS is an underdiagnosed disorder.

The CSF1R protein is an important receptor in the brain that is primarily present in microglia, the immune cells of the brain. ?We identified a different CSF1R mutation in every HDLS family that we studied,? says Dr. Rademakers. ?All mutations are located in the kinase domain of CSF1R, which is critical for its activity, suggesting that these mutations may lead to deficient microglia activity. How this leads to white matter pathology in HDLS patients is not yet understood, but we now have an important lead to study.?

?With no other disease have we found so many affected families so quickly,? says Dr. Wszolek. ?That tells me this disease is not rare, but quite common.? He adds, ?It is fantastic that you can start an investigation with a single case and end up, with the help of many hands, in what we believe to be a world-class gene discovery.?

###

Mayo Clinic: http://www.mayoclinic.org/news

Thanks to Mayo Clinic for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/116318/__Rare__brain_disorder_may_be_more_common_than_thought

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    E: 31/03 2012 - The Great Global Treasure Hunton Google Earth

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    Three-Night All-Inclusive Stay At Bel Air Collection Resort & Spa Vallarta In Mexico

    All-Inclusive Beach Resort with Slew of Perks

    Thanks to Puerto Vallarta?s west-coast location, its sunsets are especially dazzling, with every conceivable shade of red, yellow, and orange filling the sky as the sun dips below Banderas Bay. In addition to offering a prime spot for viewing the nightly display from Flamingos Beach, Bel Air Collection Resort & Spa Vallarta supplies a surfeit of memorable perks?including a sunset tea service and decadent petit fours?to complement the area?s striking natural attributes.

    Along with doling out complimentary snacks, the all-inclusive resort serves gourmet Mexican, sushi, and international fare at three onsite restaurants. In between feedings, guests can while away the hours on a chaise longue overlooking a half-moon-shaped infinity pool that overlooks, in turn, the ocean. The resort?s lavish spa indulges guests with coffee skin treatments and midnight massages on a beach dotted with tiki torches. Staff members pour colorful cocktails and glasses of wine at a sports bar and an ocean-view jacuzzi bar. At the end of the day, guests retire to standard rooms outfitted with a king-size bed and a hydro-massage bathtub to relieve tension accrued from dealings with unreliable sandcastle contractors.

    Puerto Vallarta, Mexico: Tropical Paradise with Cosmopolitan Flair

    Puerto Vallarta is perhaps Mexico?s most sophisticated vacation destination. Known simply as Vallarta, the city sizzles with cosmopolitan flair on its expansive beaches and cobblestone streets lined with trendy restaurants. A 10-block boardwalk known as the malec?n offers unobstructed ocean views as it extends from the city center, leading past fountains and landmarks such as the famous 9-foot-high statue of a boy riding a sea horse. Considered the most LGBT-friendly city in Mexico, Vallarta draws a diverse crowd of vacationers intent on relaxing during the day and living it up at night as they bounce between the city?s numerous dance clubs and bouncy castles.

    December 25, 2011, 12:46 pm

    Source: http://www.bargainez.com/deal/three-night-all-inclusive-stay-at-bel-air-collection-resort-spa-vallarta-in-mexico-127/

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    A New Generation of Nuclear Plants Amid Squabbling (ContributorNetwork)

    In a tumultuous week of events, the United States came a step closer to ushering in a new generation of nuclear power plants with the Nuclear Regulatory Commission approving a new reactor design. At the same time, according to a December 14 Reuters article, Congress got an ear full from members of that commission, who have accused their chairman of creating a toxic environment within the agency. Here are the highlights of both issues:

    * According to an article by Bloomberg, on December 14, Tokyo-based Toshiba Corp.'s Westinghouse Electric received the third of five votes from the Nuclear Regulatory Commission members to certify the design of its AP1000 reactor. Southern Co. and Scana Corp. plan to use the new reactor at existing U.S. plants. Dale Klein, former NRC chairman and chancellor for research at the University of Texas states that this action opens the door for a new generation of power plants.

    * The NRC hasn't issued a construction license for a U.S. nuclear plant since the 1979 Three Mile Island incident in Pennsylvania.

    * According to a report commissioned by environmentalist groups including Friends of the Earth and the North Carolina Waste Awareness & Reduction Network, the AP1000's design will not withstand potentially high pressure inside the reactor. The groups have vowed to take their problems with the reactor's designs to the courtroom unless NRC reconsiders. However, Bloomberg reported, the AP1000 already incorporates safety features that were prioritized by an NRC task force who examined U.S. plants after the Fukushima meltdown in Japan last March.

    * The announcement of the majority vote for certification of the design came one day after a hearing before the House Oversight and Government Reform Committee, in which strained relations between members of the 5-person commission reached a boiling point. According to Reuters, Democratic commissioners William Magwood and George Apostolakis joined Republicans Kristine Svinicki and William Ostendorff in accusing NRC chairman Gregory Jaczko of bullying people, withholding information and interfering with their access to senior staff.

    * At the two-hour hearing, Jaczko said his colleagues had "misconstrued" his intensity and suggested that a mediator might help improve communications between himself and his colleagues. He stated that this was the first time he'd heard many of these accusations.

    * The ranking Democrat on the committee, Elijah Cummings (MD) chastised the commissioners and told them he felt like he was trying to referee a fight; something he hadn't done since his kids were children.

    Source: http://us.rd.yahoo.com/dailynews/rss/environment/*http%3A//news.yahoo.com/s/ac/20111216/us_ac/10683387_a_new_generation_of_nuclear_plants_amid_squabbling

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